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BP1837 BP1837 iscS iscS alaS alaS BP3522 BP3522 BP1835 BP1835 BP1834 BP1834 BP1833 BP1833 BP0431 BP0431 moaD moaD moaC moaC trmU trmU
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BP1837Similar to Neisseria meningitidis hypothetical protein Nma0882 or Nmb0681 SW:Y882_NEIMA (Q9JR98) (74 aa) fasta scores: E(): 1.1e-10, 61.66% id in 60 aa, and to Pseudomonas aeruginosa hypothetical protein Pa1006 TR:Q9I4W7 (EMBL:AE004533) (83 aa) fasta scores: E(): 1.6e-10, 45.23% id in 84 aa; Belongs to the sulfur carrier protein TusA family. (84 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
   
 0.991
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
    0.865
BP3522
Putative membrane protein; Similar to Pseudomonas aeruginosa hypothetical protein PA5430 TR:Q9HTD6 (EMBL:AE004955) (404 aa) fasta scores: E(): 1.7e-89, 63.59% id in 401 aa, and to Rhizobium meliloti hypothetical protein SMB21550 TR:CAC49391 (EMBL:AL603645) (413 aa) fasta scores: E(): 1.9e-74, 52.81% id in 409 aa. Possible alternative translational start site.
  
  
 0.750
BP1835
Putative exported protein; No significant database matches.
  
    0.596
BP1834
Putative fimbrial protein; Similar to Escherichia coli type IV prepilin PilS TR:O88170 (EMBL:AB007463) (204 aa) fasta scores: E(): 0.62, 24.49% id in 196 aa, and to Salmonella typhi PilS protein TR:Q9ZIU9 (EMBL:AF000001) (206 aa) fasta scores: E(): 0.71, 29.78% id in 188 aa.
  
    0.580
BP1833
Putative general secretion pathway protein (Pseudogene); 11 bp insertion in pertussis relative to parapertussis and bronchiseptica.
       0.511
BP0431
Putative molybdopterin oxidoreductase; Similar to Salmonella typhimurium thiosulfate reductase precursor PhsA SW:PHSA_SALTY (P37600) (758 aa) fasta scores: E(): 6.8e-17, 23.279% id in 799 aa, and to Archaeoglobus fulgidus molybdopterin oxidoreductase, molybdopterin binding subunit Af1203 TR:O29065 (EMBL:AE001021) (741 aa) fasta scores: E(): 2.9e-26, 26.489% id in 789 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
  
 0.491
moaD
Similar to Escherichia coli molybdopterin converting factor, subunit 1 MoaD or Chla4 or ChlM or B0784 SW:MOAD_ECOLI (P30748) (81 aa) fasta scores: E(): 4.9e-05, 46.34% id in 82 aa.
   
 
 0.465
moaC
Molybdenum cofactor biosynthesis protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
     
 0.434
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
     
 0.434
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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